O substanţă vegetală ar putea fi soluţia pentru cancerul de piele

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#1 Cornelia Vodoiu 5.09.2009 11:35

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Ma ocup de EDUCATIA SI PREVENTIA CANCERULUI, inclusiv a CANCERULUI SPIRITUAL pentru a aduce la lumina FAMILIA ROMANEASCA SI SCOALA ROMANEASCA. Vin cu o completare:« Sept.2, 2009 – People with advanced skin and brain cancers – untreatable by current methods –improve after treatment with a new oral drug called a « hedgehog inhibitor ». Hedgehog is one of the drug hottest new anticancer targets. During embryonic development and childhood , the signaling molecule nicknamed « hedgehog » spurs growth processes. But the body turns it off during adulthood. When hedgehog isn’t turned off, it promotes the growth of cancer cells. An experimental drug code –named « GDC -0449 » by developer Genentech blocks hedgehog. Can it fight cancer ? Some cancer types are particularly dependent on hedgehog. One is « basal cell carcinoma » the most common skin cancer in early disease, metastatic has no standard treatment and usually is rapidly fatal. Can « GDC-0449 » help ? In a Genentech –funded study , Daniel D.Von Hoff, MD, of Scottsdale Healthcare and colleagues gave the drug to 33 patients with inoperable metastatic or locally advanced « basal cell carcinoma ». « The overall response rate was 55% with a remarkable response rate of 50% in 18 patients with metastatic disease », University of Michigan researchers Andrzej A. Dlugosz, MD, and Moshe Talpaz < MD< note in an editorial accompanying the study in the Sept.2 online edition of « The New England Journal of Medicine » .Only four of the patients had continued progression of their cancers over the course of the 10-month study. There were relatively few adverse events linked to the treatment. In another Genentech –funded study published in the same issue of « The New England Journal Of Medicine », Johns Hopkins researcher Charles M.Rudin, MD, PhD, and colleagues report the treatment of a brain cancer –medulloblastoma –with « GDC-0449 » . Dlugosz and Talpaz note that as a future cancer treatment , « GDC-0449 » likely will be used in combination with surgery and other treatments. Other companies are working on hedgehog inhibitors. There is evidence that this class of drug may be helpful in many different cancer types. SOURCES : Dlugosz, A.A. And Talpaz M. « The New England Journal of Medicien, « online edition, Sept.2, 2009 ; Von Hoff, D.D. « the New England Journal of Medicine » ,online edition , Sept.2, 2009 ; Rudin , C.M., « The New England Journal of Medicine », online edition, Sept.2, 2009. » Daniel J.DeNoon, Louise Chang, MD – « Hedgehog Drug Helps Late –Stage Cancers ». » Multa sanatate! Cu respect, profesor+chimist+ofiter Cornelia Vodoiu, promotia de absolventi 1982.

 

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