Un nou tratament pentru scleroza în plăci

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#1 gandul.info 20.08.2009 09:13

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Un medicament folosit în tratarea hipertensiunii arteriale este eficient şi în tratarea sclerozei în plăci, putând să împiedice sau chiar să inverseze efectele maladiei, care este caracterizată prin paralizia muşchilor, susţin oamenii de ştiinţă de la Facultatea de Medicină din cadrul Universităţii Stanford din California.

 

#2 Cornelia Vodoiu 20.08.2009 09:13

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sanatatea este cea mai mare bogatie. pentru orice boala trebuie sa exista profilaxie. [« multiple sclerosis may be treated with inexpensive hypertention drug.turning serendipity into science, researchers at the stanford university school of medicine have found a link , in mice and human brain tissue, between high blood pressure and multiple sclerosis. their findings suggest that a safe, inexpensive drug already in which use for high blood pressure may have therapeutic value in multiple- sclerosis as well. while neurology professor lawrence steinman, md, senior author of the new study, cautioned that extensive clinical trial work is needed to determine if the drug , known as « lisinopril » can do in humans what it does in mice, he is excited that « we were able to show that all the targets for « lisinopril » are there and ready for therapeutic manipulation in the multiple-sclerosis lesions of human patients. without that, this would be just another intriguing paper about what’s possible in the mouse ». the paper was published online aug.17 by the « proceedings of the national academy of sciences ». the genesis for the paper can be traced to about seven years ago, when steinman learned he had high blood pressure. his doctor put him on « lisinopril » , which is used by millions of people all over the world, and has an excellent safety profile. chagrined, steinman went home and, researcher that he is , immediately did a google search on the drug. (steinman is a renowned multiple- sclerosis investigator whose earlier work on the inflammatory features of the disease spurred development of a blockbuster class of anti-inflammatory multiple-sclerosis therapeutics. the drug « natalizumab » ,marketed under the trade name « tysabri », is one). multiple –sclerosis is a chronic and occasionally lethal autoimmune disease in which the body’s immune system mounts recurring assaults on the myelin sheathing of nerve cells in the brain .this causes nerves to malfunction and can lead to blindness and paralysis. both multiple –sclerosis and atherosclerosis involve inflammatory processes. the team also found that « lisinopril » administration reduced numerous molecular measures of inflammation that accompany multiple-sclerosis in humans and its analog in the animal model. but, importantly , the drug didn’t inhibit the mice’ overall immune competence. source : bruce goldman, stanford university medical center. » ](medical news today).

 

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